Nuclear Medicine and Preclinical Imaging Systems
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nanoScan PET/CT

small animal PET/CT in vivo imagerPowerful high sensitivity, high resolution and fully integrated small animal PET/CT system

The nanoScan PET/CT small animal in vivo imager offers user-friendly imaging and the broadest range of supported applications in one simple to use, high-end PET/CT system. The nanoScan PET/CT products are equipped with PET and CT detectors as well as data processing and reconstruction chains that are widely considered to be among the most advanced in the industry.


The nanoScan PET/CT ensures the best imaging resolution with the highest sensitivity and unmatched image quality in whole body small animal examinations.


Summary of Key Benefits
  • Highest resolution PET subsystem with outstanding quantification:
    • ≤ 0.7 mm (measured with Derenzo phantom and reconstructed with Tera-Tomo™ 3D PET engine)
    • Uniform resolution over the FOV
    • Quantitative accuracy is better than 97%
  • Imaging capability for larger animals, i.e. monkeys with 16cm gantry bore diameter and 12 cm Transaxial Field of View (TFOV) in both modalities
  • Open tunnel PET/CT construction: backdoor access to the animal
  • Fully integrated with MultiCell™, the complete small animal environment to provide vital support functions to lab animals during the imaging process
  • Integrated cardiac and respiratory gating capabilities for selected modalities
  • Stand-alone (individual) use is possible for each modality
  • Compatible with nanoScan® PET/MRI, NanoSPECT/CT® and NanoPET/CT®
  • Compliant with CE, DICOM, CFR 21 industry standards
  • Compact and easy-to-use design
Bone imaging in Mouse
Selected Features for PET subsystem
  • Superior PET detector characteristics:
    • High-density, ultra-small detectors with the finest LYSO detector elements and thus the smallest pitch
    • Increased crystal thickness for highest sensitivity
  • Measure even the finest details: Tera-Tomo™ 3D PET reconstruction engine brings PET resolution close to the physical limits of the technology with outstanding quantification, and improved signal recovery and signal-to-noise ratio:
    • Features Monte Carlo system matrix modeling and Depth of Interaction correction; incorporates attenuation, scatter, positron range, random and dead time corrections.
    • Reconstruction running on multiple GPUs (Graphical Processing Units) delivering shorter computation time
  • Perform Acquisition and Reconstruction simultaneously with the powerful workstations including DICOM server and multi-modality display and analysis suite


420g weight, 7.21MBq/0.2ml, start pi.1h, 30min/ 1FOV, 1:5Selected Features for CT subsystem

The CT subsystem can be used independently for whole-body imaging.
It is possible to image the largest variety of species currently used in research including larger animals or whole body mouse scans in one bed position. The system features a very large detector surface and large bore with helical or spiral scanning, variable zoom (up to 8) and high power X-ray source (up to 80W).

  • Broadest range of CT applications: Ultrafast and ultralow dose CT with variable zoom up to x7.6 magnification to visualize even the smallest organs or in-vitro samples up to 120mm FOV
    • Perform a whole-body mouse scan in 2 minutes – have the result instantly with 80 micron voxel size
    • Closest source to object distance for in-vivo imaging: extra small objects imaging
  • Tomographic information is ready at the end of scan*: on the fly real time reconstruction is enabled by multi-GPUs (* with applicable settings)
  • Optimized X-ray exposure dose to the animals and faster data acquisition due to stronger X-ray tube, increased detector area, sensitivity and better filtering
  • Automated calibration processes
  • Improved safety functions (gantry rotation position is stored, optimized X-ray ramp-up and run-up to ensure prolonged tube life)
System Design
  • Spiral mode with extended axial field of view of 28 cm for both modalities

    64 Cu-Cetuximab-Fab whole-body imaging of a NMRI Nu/Nu mouse with FaDu tumor xenograft 48 hours post i.v. injection of 34 MBq labeled Fab. Imaging duration 30 min, imaged actual activity cca. 3 MBq. Two plane sections and a MIP. Besides heterogeneous uptake in the tumor, kidney cortex and liver is visible, too. Image courtesy of Helmholtz-Zentrum Dresden Rossendorf, Germany

  • Accessability to the animal during scanning: Flat front cover with minimal dead area in both axial and transaxial directions
  • Fully automated animal positioning based on CT scout; manual adjustment is also supported
  • The system is equipped with remote access capability for service and remote diagnostics
  • Safety switches are both in the acquisition and control room allowing immediate stop of the examination
  • Integrated touchscreen monitor mounted on the gantry allows the user to control bed movements, gantry rotation, positioning for CT zoom and positioning related calibrations and settings